Neurocristopathy

 

The stage of Embryo development during which there is abnormal expression, migration, differentiation, and necrosis of the Neural Crest Cells (NCC’s) neurological disorders. Neural Crest Cells arise from the developing embryo of vertebrates and is called the Fourth germ layer. There are four categories of Neural Crest: Trunk Neural Crest (tNCC), Cardiac Neural Crest (carNCC), Cranial Neural Crest (cNCC), and Sacral and Vagal Neural Crest. Some notable disorders of neural crest include Albinism, Neuroblastoma, Melanoma, Di George Syndrome and Hirschsprung Disease. Various disorders of thyroid, ear, skin, heart, craniofacial and digestive system are attributed to the malformation of a proper neural crest. Neuroblastoma can be treated by surgical resection. Folate deficiencies during conception period can lead to congenital abnormalities and; hence it is recommended to have sufficient intake of folate in food. Craniofacial defects are congenital with abnormalities in the growth of facial and skull bones. Researches are active in this area using rDNA technology to find a cure for patients with Craniofacial defects.

 

  • Track 1-1 Neuroblastoma
  • Track 2-2 Neural Crest Development( Embryology)
  • Track 3-3 Abnormalities of Nervous System
  • Track 4-4 Craniofacial Defects

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